- Colon (Argentina) (Colón) - a city in Entre Rios, in Mesopotamia (Argentina)
- Colon (Panama) (Colón) - a city
- Colon (province) (Colón) - a province
- Colon (Nebraska) - a village in Saunders County, in the Metro Omaha region of Nebraska
- Colon (Michigan) - a township and a village within that township, in St. Joseph County, West Michigan
- Colón (Venezuela) - a town
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